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Understanding the 4 M’s: Methylation, Metabolism, Mitochondria, and Microbiome

Understanding the 4 M’s: Methylation, Metabolism, Mitochondria, and Microbiome

November 22, 2025
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Understanding the 4 M's

The following is an actual transcript. We do our best to make sure the transcript is as accurate as possible, however, it may contain spelling or grammatical errors.  We suggest you watch the video while reading the transcript.

Join Dr. Monika Buerger in this insightful video where she expands on the interconnected roles of methylation, mitochondria, metabolism, and the microbiome. Dr. Monika highlights the recent buzz around leucovorin use for autism and the importance of individualized biochemistry over solely focusing on M-T-H-F-R gene mutations. She emphasizes a holistic approach to health, especially for children, involving a balanced diet, stress reduction, and supporting the microbiome. Watch till the end to learn more about managing the microbiome and enhancing the overall health and wellbeing of future generations.

00:00 Introduction to the Four M’s
00:15 Understanding Methylation
00:58 The Role of M-T-H-F-R Gene
02:07 Treat the Person, Not the Gene
05:03 Supporting the Microbiome
07:37 Practical Tips for a Healthy Lifestyle
08:47 Conclusion and Further Learning

Learn more at: https://neurodevacademy.com

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Dr. Buerger is recognized as a leading authority in pediatrics both within the chiropractic profession as well as in the world of pediatrics outside the profession. She is a pioneer in neurosensory integration and neurodevelopment. Recognized as a true authority, her work is included in all three volumes of the Pediatric Chiropractic textbook.

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